For over a century we have attempted to understand human aesthetic experience using scientific methods. A typical experiment could be described as reductive and quasi-psychophysical. We vary some aspect of the stimulus and systematically measure some aspect of the aesthetic response. The limitations of this approach can be categorized as problems on the Y axis and the X axis. The most enigmatic components of aesthetic experience include inclination to cry, aesthetic rapture, a sense of the sublime, and intense fascination. However, (...) we cannot evoke these 'hot' aesthetic emotions in the lab, at least not with well controlled stimuli on multiple trials. We thus resort to measuring cold, cognitive preference ratings. There are also problems on the X axis. The reductive psychophysical approach explicitly assumes that there are lawful relations between different stimulus dimensions and preferences. It also tacitly assumes that these dimensions are independent and orthogonal. The second assumption is implausible. Whatever stimulus-preference laws we discover are likely to be twisted and modulated when another dimension is added to the stimuli. This 'gestalt nightmare' has long been recognized, but never resolved. This matters, because human aesthetic faculties are probably tuned to the balance and relationship of parts which make up a whole and are indifferent to the parts presented in isolation. I conclude that the future of scientific aesthetics depends on how successfully we can transcend reductive, quasi-psychophysical approaches. (shrink)

Ausgehend von einer postulierten Abstammung der verschiedenen Gymnospermengruppen und der Angiospermen von Progymnospermen werden die Semophylesen der Samenanlagen und deren „Hüll- und Schutzorganen” eingehend besprochen. Das innere Integument ist phylogenetisch wohl aus verwachsenen sterilen Megasporangien entstanden, das aussere ist das Homologon der Cupula der Samenfarnen und ein Achsengebilde.Die dritte Hülle — die interseminalen Schuppen bei den Bennettiteen, die Chlamys bei den Chlamydospermen, die Fruchtknotenwand bei einigen Angiospermengruppen wie Pandanaceen und Cyperaceen, und der Arillus bei Angiospermen mit karpellaten Gynoezien — ist (...) wahrscheinlich aus reduzierten Samenanlagen hervorgegangen. Die vierte, aus sterilen brakteenartigen Phyllomen entstanden, hat in verschiedenen Kombinationen mit fertilen Achsen, die karpellaten Fruchtknoten der Angiospermen gebildet.Die Herkunft der Blütenpflanzen von chlamydospermen- und bennettiteen-ähnlichen Vorfahren wird sehr wahrscheinlich da Übergänge zwischen den „nackten” Samenanlagen vomGnetum-Typ und sogenannten pseudomonomeren Griffeln von Angiospermen vorliegen.En basant la phylogénie de plusieurs groupes de Gymnospermes et d'Angiospermes sur une descente des Progymnospermes du Devonien Supérieur , les sémophylèses des ovules et de ses couches protectrices ont été discuté.Le tégument interne très probablement représente une groupe de mégasporanges stériles fusés, le tégument externe est l'homologue des cupules des ptéridospermes et d'origine axillaire. La troisième couche — les écailles interséminales chez les Bennettitales, la chlamys chez les Chlamydospermes, le paroi de l'ovaire chez quelques Angiospermes comme les Pandanacées, les Piperacées..., l'arille de l'ovule dans les ovaires carpellaires des Angiospermes — est probablement l'homologue d'un nombre d'ovules steriles. La quatrième couche, constituée de phyllomes steriles, s'est associée avec des axes ovulifères en formant les pistils carpellaires des Angiospermes. L'origine des Angiospermes des ancêtres d'un type Chlamydosperme-Bennettitale est indiqué par la morphologie transitoire de quelques ovaires soi-disant „pseudo-monomères” liant les ovules „nues” du typeGnetum avec les pistils du type des Piperacées, Chloranthacées etc. (shrink)

A critical appraisal of the theories founded on the theorem of the multiaxial flower , shows an evolution fromWettstein's original version of 1907 to various hypotheses founded on the the same theme and partly derived from the Wettsteinian doctrine. A number of circumstances such as semantic inconsistencies, but principally the choice of inadequate archetypes, prevented the success of the theory of a polystachyous floral region, because the deductions and interpretations emanating from this concept were not sufficiently convincing to defeat the (...) opposed theory of the uniaxial euanthous flower or anthostrobilus hypothesis. Only after the amendation of the theory of a multiaxial reproductive region on the basis of the anthocorm concept can one arrive at a plausible idea of the evolution of the angiospermous flower which is compatible with all aspects of the phylogeny of the Flowering Plants , and with the floral morphology and anatomy of the various kinds of flowers.Eine kritische Bewertung der Theorien die auf dem Theorem der mehrachsigen Blüte gegründet worden sind zeigt die Entwicklung von einer vonWettstein in 1907 vorgeschlagenen Originalversion zu mehreren, teilweise davon abgeleiteten, Theorien über das Thema der Entstehung der Angiospermenblüte. Verschiedene Umstände, wie z.B. semantische Widersprüche, aber in erster Stelle die Wahl eines inadäquaten Prototypus, verhinderten anfänglich den Erfolg der Hypothese eines mehrachsigen Blütenbereiches, weil es den hervorgehenden Schlussfolgerungen und Deutungen zu viel an Ueberzeugungskraft mangelte um die gegnerische Theorie der einachsigen Ranalesblüte oder Anthostrobilushypothese endgültig zu verdrängen. Erst die Ergänzung der Theorie einer vielachsigen Blüte ermöglichte die plausibele Darstellung der Evolution der Angiospermenblüte, welche Erörterung in befriedigender Weise in Uebereinstimmung ist mit allenA spekten der Phylogenie der Blütenpflanzen , und auch mit den morphologischen and anatomischen Verhältnissen bei Blüten jeder Art im Anklang ist.Une évaluation critique des différentes théories fondées sur le théorème de la fleur pluriaxiale montre une évolution qui commence avec une version originale proposée parWettstein en 1907 et qui mène à plusieurs théories, partiellement dérivées de l'idée wettsteinienne, sur le thème de l'origine de la fleur. Quelques circonstances, comme par exemple des contrariétés sémantiques, mais surtout la choix d'un prototype inadéquat, ont prévenu au début le triomphe de l'hypothèse d'une région florale pluriaxiale, puisque les conclusions et les interprétations qui provenaient de cette théorie étaient privées de toute conviction pour suppléer la théorie opposée de la fleur ranalienne et uniaxiale . Une explication recevable de l'évolution de la fleur angiospermique qui harmonise avec tous les aspects de la phylogénie des plantes floriales , et aussi avec les conditions morphologiques et anatomiques de toutes sortes de fleurs, ne gagnait de terrain qu'après le perfectionnement de la théorie de la fleur pluriaxiale. (shrink)

The different aspects of floral evolution—Angiosperm descent, floral morphology and pollination ecology—are discussed on the basis of the anthocorm theory of the angiospermous flower. Opposed ideas are critically compared and rejected mainly on account of several inconsistencies and flaws in old floral concepts. Floral evolution passed from a very early phase of dicliny, anemophily and aphananthy of the anthocorm to a phase of incipient entomophily soon associated with a partial sex reversal within the anthocorm. This second phase culminated in the (...) monoclinous and primarily zoophilous flower types, whereas other floral types, more particularly the primarily anemophilous, diclinous flowers, are the direct descendants of the anthocorms of the initial phase. The second phase gave rise to at least two morphologically different flower types and two separate semophyletic lines of floral evolution , in each of which the primary zoophily is almost always associated with the development of intrafloral semaphylls usually of androecial derivation. Early flower types were aphananthous and clearly anthocormoid and assumed the morphology and other characteristics of a true flower by contractions, condensations, readjustments, oligomerisations, reductions and modifications leading to the great variety of adaptive floral patterns.Divers aspects de l'évolution de la fleur — à savoir la descendance des Angiospermes, la morphologie de la fleur, et l'écologie de la pollination — sont discutés à partir de l'hypothèse florale de l'anthocorme. Les opinions opposées, après d'être comparées et critisées, sont rejetées principalement à cause des inconséquences et inconsistances des anciens théorèmes morphologiques concernant l'origine de la fleur. L'évolution de la fleur commençait avec une phase d'antan de diclinie, anémophilie et aphananthie, et s'avançait graduellement dans la direction d'une phase entomophilique initiale, bientôt accompagnée d'un renversement de sexe partiel à l'intérieur de l'anthocorm. La deuxième phase culminait vers les types florals monoclines avec zoophilie primaire pendant que des autres types florals, particulièrement les fleurs diclines avec anémophilie primaire, sont les descendants directs du stade initiale de l'anthocorme. A partir de la phase II , au moins deux types florals différents et aussi deux sémophylèses florals séparés se développaient. Dans chacun de ses phases III et III A la zoophilie primaire est presque toujours accouplée avec l'origine des sémaphylles intrafloraux le plus souvent dérivés des étamines. Les anciens types des fleurs ayant été aphanantique et au début encore nettement anthocormoïdes , graduellement prenaient la forme d'une des plusieurs types floraux adaptifs par une contraction de l'axe florale et par l'entassement, l'oligomérisation et la modification des pièces de la fleur.Die drei Aspekte der Evolution der Blüte — die Abstammungsgeschichte der Angiospermen, Blütenmorphologie und Bestäubungsökologie — werden, ausgehend von der Anthokormtheorie der Angiospermenblüte, eingehend besprochen. Entgegengesetzte Meinungen werden kritisch verglichen und hauptsächlich auf Grund mehrerer Strittigkeiten und Fehler der älteren blütenmorphologischen Axiomen abgelehnt. Die Evolution der Blüte fing an mit einer frühen Phase mit Diklinie, Anemophilie und Aphananthie des Anthokorms und schritt allmählich weiter in die Richtung von beginnender Entomophilie, bald mit einer partiellen Geschlechtsinversion innerhalb des Anthokorms zusammengehend. Diese zweite Phase kulminierte in den monoklinen und primär zoophilen Blütentypen, während andere Blütengestalten, besonders die primär anemophilen und diklinen Angiospermenblüten, die unmittelbaren Abkömmlinge der Initialphase des Anthokorms sind. Aus der zweiten Phase entwickelten sich wenigstens zwei morphologisch differenzierte Blütenformen und auch zwei geschiedene Blütensemophylesen , in jeder die primäre Zoophilie fast immer verbunden ist mit der Entwicklung von intrafloralen und meistens von Staubblättern angeleiteten Semaphyllen . Die frühen Blütentypen waren aphanantisch und anfänglich noch deutlich anthokormoid und nahmen allmählich die entgültige Gestalt von einer der vielen adaptiven Blütentypen an durch eine Verkürzung der Blütenachse, und durch ein Zusammendrängen, Oligomerisation und Abänderung der Blütenteile. (shrink)

Background: The factors influencing parents’ willingness to enroll their children in biobanks are poorly understood. This study sought to assess parents’ willingness to enroll their children, and their perceived benefits, concerns, and information needs under different consent and data-sharing scenarios, and to identify factors associated with willingness. Methods: This large, experimental survey of patients at the 11 eMERGE Network sites used a disproportionate stratified sampling scheme to enrich the sample with historically underrepresented groups. Participants were randomized to receive one of (...) three consent and data-sharing scenarios. Results: In total, 90,000 surveys were mailed and 13,000 individuals responded (15.8% response rate). 5737 respondents were parents of minor children. Overall, 55% (95% confidence interval 50–59%) of parents were willing to enroll their youngest minor child in a hypothetical biobank; willingness did not differ between consent and data-sharing scenarios. Lower educational attainment, higher religiosity, lower trust, worries about privacy, and attitudes about benefits, concerns, and information needs were independently associated with less willingness to allow their child to participate. Of parents who were willing to participate themselves, 25% were not willing to allow their child to participate. Being willing to participate but not willing to allow one’s child to participate was independently associated with multiple factors, including race, lower educational attainment, lower annual household income, public health care insurance, and higher religiosity. Conclusions: Fifty-five percent of parents were willing to allow their youngest minor child to participate in a hypothetical biobank. Building trust, protecting privacy, and addressing attitudes may increase enrollment and diversity in pediatric biobanks. (shrink)

A fresh, daring, and genuine alternative to the traditional story of scientific progress Explaining the world around us, and the life within it, is one of the most uniquely human drives, and the most celebrated activity of science. Good explanations are what provide accurate causal accounts of the things we wonder at, but explanation's earthly origins haven't grounded it: we have used it to account for the grandest and most wondrous mysteries in the natural world. Explanations give us a sense (...) of understanding, but an explanation that feels right doesn't mean it is true. For every true explanation, there is a false one that feels just as good. A good theory's explanations, though, have a much easier path to truth. This push for good explanations elevated science from medieval alchemy to electro-chemistry, or a pre-inertial physics to the forces underlying nanoparticles. And though the attempt to explain has existed as long as we have been able to wonder, a science timeline from pre-history to the present will reveal a steep curve of theoretical discovery that explodes around 1600, primarily in the West. Ranging over neuroscience, psychology, history, and policy, Wondrous Truths answers two fundamental questions-Why did science progress in the West? And why so quickly? J.D. Trout's answers are surprising. His central idea is that Western science rose above all others because it hit upon successive theories that were approximately true through an awkward assortment of accident and luck, geography and personal idiosyncrasy. Of course, intellectual ingenuity partially accounts for this persistent drive forward. But so too does the persistence of the objects of wonder. Wondrous Truths recovers the majesty of science, and provides a startling new look at the grand sweep of its biggest ideas. (shrink)

While research has focused on the role of racism in (re)producing ethnic/racial inequalities in education, there is very little research that investigates how variability in minority students’ responses to racism can be explained. By using an ecological approach to integrate existing research on actors’ responses to racism, this study finds that researchers have generally neglected factors and processes situated at the micro- and meso-levels of analysis. Qualitative interview data with Turkish–Cypriot children enrolled in schools in the predominantly Greek-speaking part of (...) the Republic of Cyprus are used to investigate their strategies in response to racism and the factors that explain the observed variability in their responses. The findings suggest the importance of and interactions between factors situated at different levels of analysis, including the level of organizations and social groups and face-to-face interactions in explaining variability in young people’s responses to racism. (shrink)

Volume 46, Issue 6, November 2020, Page 727-743.

The question of what makes someone the same person through time and change has long been a preoccupation of philosophers. In recent years, the question of what makes ordinary or lay people judge that someone is—or isn’t—the same person has caught the interest of experimental psychologists. These latter, empirically oriented researchers have sought to understand the cognitive processes and eliciting factors that shape ordinary people’s judgments about personal identity and the self. Still more recently, practitioners within an emerging discipline, experimental (...) philosophical bioethics or “bioxphi”—the focus of this chapter—have adopted a similar aim and employed similar methodologies, but with two distinctive features: (a) a special concern for enhanced ecological validity in the examples and populations studied; and (b) an interest in contributing to substantive normative debates within the wider field of bioethics. Our aim in this chapter is to sample illustrative work on personal identity in bioxphi, explore how it relates to studies in psychology covering similar terrain, and draw out the implications of this work for matters of bioethical concern. In pursuing these issues, we highlight recent work in bioxphi that includes the perceived validity of advance directives following neurodegeneration, the right of psychologically altered study participants to withdraw from research, how drug addiction may cause one to be regarded by others as “a completely different person,” the effect of deep-brain stimulation on perceptions of the self, and the potential influence of moral enhancement interventions on intuitive impressions of a person’s character. (shrink)

Issues of resource allocationResource allocation, triageTriage, and rationingRationing decisions are common in the context of disasters and public healthPublic health emergencies, such as pandemics. However, to date, the majorityMajority of the literature focuses on an adult population with very little attention given to a pediatric population or to a population that may be mixed: adults and children. Furthermore, decisions of rationingRationing scarce resources do not only occur during disasters and other wide-scale emergencies. Such decisions are commonplace in pediatric organ transplantation (...) and can creep into areas of experimental medicine, such as xenotransplantation. This chapter explicates differences between pediatric and adult triageTriage decisions by first looking at the trifold issues of resource allocationResource allocation, triageTriage, and rationingRationing decisions mainly in the context of a disaster situation or public healthPublic health emergency. However, the issues of pediatric organ transplantation, health disparitiesHealth disparities, and experimental medicine will also be covered. (shrink)

On the ethics of extending human life: healthy people have a right to carry on livingHumanity has long demonstrated a paradoxical ambivalence concerning the extension of a healthy human lifespan. Modest health extension has been universally sought, whereas extreme health extension has been regarded as a snare and delusion—a dream beyond all others at first blush, but actually something we are better off without. The prevailing pace of biotechnological progress is bringing ever closer the day when humanity will be able (...) to act on the latter view by rejecting a clear and present opportunity for much longer healthy lives. Indeed, some biogerontologists contend that that day has already arrived, to the extent that our hesitation in embarking on a vigorous “war on ageing” is already delaying the point at which a cure for ageing will be developed. Here I consider whether our present caution concerning the wisdom of truly curing ageing is likely to survive the increased scrutiny that it will receive in coming years as a result of these technical advances. I conclude that it will not, because of its irreconcilability with values that are more deeply held by the large majority of humanity than any values that argue against the quest for a cure. I further conclude that all the major current reasons given for not curing ageing are mere crutches to help us cope with the immutability of ageing that we have been brought up to accept. Our failure to set aside such irrationality is already shortening potential longevity—quite probably of those already alive today—to a staggering degree. Once we realise this, our determination to consign human ageing to history will be second …. (shrink)

Background: The traditional approach to resolving ethics concerns may not address underlying organisational issues involved in the evolution of these concerns. This represents a missed opportunity to improve quality of care “upstream”. The purpose of this study was to understand better which organisational issues may contribute to ethics concerns. Methods: Directed content analysis was used to review ethics consultation notes from an academic children’s hospital from 1996 to 2006 (N = 71). The analysis utilised 18 categories of organisational issues derived (...) and modified from published quality improvement protocols. Results: Organisational issues were identified in 68 of the 71 (96%) ethics consult notes across a range of patient settings and reasons for consultation. Thirteen of the 18 categories of organisational issues were identified and there was a median of two organisational issues per consult note. The most frequently identified organisational issues were informal organisational culture (eg, collective practices and approaches to situations with ethical dimensions that are not guided by policy), policies and procedures (eg, staff knows policy and/or procedural guidelines for an ethical concern but do not follow it) and communication (eg, communication about critical information, orders, or hand-offs repeatedly does not occur among services). Conclusions: Organisational issues contribute to ethical concerns that result in clinical ethics consults. Identifying and addressing organisational issues such as informal culture and communication may help decrease the recurrence of future similar ethics concerns. (shrink)

We define our conscious experience by constructing narratives about ourselves and the people with whom we interact. Narrative pervades our lives--conscious experience is not merely linked to the number and variety of personal stories we construct with each other within a cultural frame, but is subsumed by them. The claim, however, that narrative constructions are essential to conscious experience is not useful or informative unless we can also begin to provide a distinct, organized, and empirically consistent explanation for narrative in (...) relation to consciousness. Understanding the role of narrative in determining individual and collective consciousness has been elusive from within traditional academic frameworks. This volume argues that addressing so broad and complex a problem requires an examination from outside our insular disciplinary framework. Such an open examination would be informed by the inquiries and approaches of multiple disciplines. Recognition of the different approaches to examining personal stories will allow for the coordination of how narrative seems, with what mental labor it does, and how it is realized. Only by overcoming the boundaries erected by multiple theoretical and discursive traditions can we begin to comprehend the nature and function of narrative in consciousness. Narrative and Consciousness brings together essays by exceptional scholars and scientists in the disciplines of literary theory, psychology, and neuroscience to examine how stories are constructed, how stories structure lived experience, and how stories are rooted in material reality. The specific topics addressed include narrative in the development of conscious awareness; autobiographical narrative, fiction and the construction of self; trauma and narrative disruptions; narrative, memory and identity; and the physiological and neural substrate of narrative. It is the editors' hope that the multidisciplinary nature of this collection will challenge the reader to move beyond disciplinary confines and toward a coherent interdisciplinary dialogue. (shrink)

An appropriate kind of curved Hilbert space is developed in such a manner that it admits operators of $\mathcal{C}$ - and $\mathfrak{D}$ -differentiation, which are the analogues of the familiar covariant and D-differentiation available in a manifold. These tools are then employed to shed light on the space-time structure of Quantum Mechanics, from the points of view of the Feynman ‘path integral’ and of canonical quantisation. (The latter contains, as a special case, quantisation in arbitrary curvilinear coordinates when space is (...) flat.) The influence of curvature is emphasised throughout, with an illustration provided by the Aharonov-Bohm effect. (shrink)

This study investigates the ability of individuals with psychopathy to perform passive avoidance learning and whether this ability is modulated by level of reinforcement/punishment. Nineteen psychopathic and 21 comparison individuals, as defined by the Hare Psychopathy Checklist Revised (Hare, 1991), were given a passive avoidance task with a graded reinforcement schedule. Response to each rewarding number gained a point reward specific to that number (i.e., 1, 700, 1400 or 2000 points). Response to each punishing number lost a point punishment specific (...) to that number (i.e., the loss of 1, 700, 1400 or 2000 points). In line with predictions, individuals with psychopathy made more passive avoidance errors than the comparison individuals. In addition, while the performance of both groups was modulated by level of reward, only the performance of the comparison population was modulated by level of punishment. The results are interpreted with reference to a computational account of the emotional learning impairment in individuals with psychopathy. (shrink)

IPCC SPECIAL REPORT ON CLIMATE CHANGE AND LAND (SRCCL) -/- Chapter 3: Climate Change and Land: An IPCC special report on climate change, desertification, land degradation, sustainable land management, food security, and greenhouse gas fluxes in terrestrial ecosystems.

Earp, Lewis, and Hart make a comprehensive and compelling argument for ending the “war on drugs,” highlighting the importance of both ending the criminalization of people who use drugs, and...

Previous research has found that funding disparities are driven by applications’ final impact scores and that only a portion of the black/white funding gap can be explained by bibliometrics and topic choice. Using National Institutes of Health R01 applications for council years 2014–2016, we examine assigned reviewers’ preliminary overall impact and criterion scores to evaluate whether racial disparities in impact scores can be explained by application and applicant characteristics. We hypothesize that differences in commensuration—the process of combining criterion scores into (...) overall impact scores—disadvantage black applicants. Using multilevel models and matching on key variables including career stage, gender, and area of science, we find little evidence for racial disparities emerging in the process of combining preliminary criterion scores into preliminary overall impact scores. Instead, preliminary criterion scores fully account for racial disparities—yet do not explain all of the variability—in preliminary overall impact scores. (shrink)

The goal of perception is to infer the most plausible source of sensory stimulation. Unisensory perception of temporal order, however, appears to require no inference, since the order of events can be uniquely determined from the order in which sensory signals arrive. Here we demonstrate a novel perceptual illusion that casts doubt on this intuition: in three studies (N=607) the experienced event timings are determined by causality in real-time. Adult observers viewed a simple three-item sequence ACB, which is typically remembered (...) as ABC (Bechlivanidis & Lagnado, 2016), in line with principles of causality. When asked to indicate the time at which events B and C occurred, points of subjective simultaneity shifted so that the assumed cause B appeared earlier and the assumed effect C later, despite full attention and repeated viewings. This first demonstration of causality reversing perceived temporal order cannot be explained by post-perceptual distortion, lapsed attention, or saccades. (shrink)

Consumer involvement in clinical research is an essential component of a comprehensive response during emergent health challenges. During the COVID-19 pandemic, the moderation of research policies and regulation to facilitate research may raise ethical issues. Meaningful, diverse consumer involvement can help to identify practical approaches to prioritize, design, and conduct rapidly developed clinical research amid current events. Consumer involvement might also elucidate the acceptability of flexible ethics review approaches that aim to protect participants whilst being sensitive to the challenging context (...) in which research is taking place. This article describes the main ethical challenges arising from pandemic research and how involving consumers and the community could enable resolution of such issues. (shrink)